ALNY max pain for the Oct 16, 2026 expiry is $240. The last price, $219.89, is 8.4% below it. Call wall $250 · put floor $200.
What the institutional money is doing on ALNY right now — dark pool, options positioning, and where the news and the money disagree. Free.
The money right now
Dark pool share
42.4% (market avg 49%)
Dark pool volume vs its norm
0.9×
Short share of that
48.8% (norm 69%)
Dark pool share: Only 49% vs a 69% norm of the off-exchange volume was short
Off-exchange prints never touch the public book, so they move size without moving the quote. That is the point of using them. Size was ordinary, but the sell side was light within it — not aggressive accumulation, yet no real selling pressure either.
Source: FINRA · Mon 10/5 close
What it means: ALNY's options market shows a bullish lean—more calls than puts in both standing positions and recent trading flow—but positioning is thin and squeeze pressure is minimal. Off-exchange volume sits below its own 20-day norm, and short activity there is unusually LOW (49% vs. a 68% average), suggesting institutions are not aggressively hedging or trimming; the stock trades near max pain (240), leaving room to both the call wall (250) and put floor (200).
News vs the money
Alnylam launches patient education campaign for heart ATTR disease
The campaign announcement arrives as options traders hold a call-heavy bias, but no new large positions opened on the news, and off-exchange short activity remains well below the stock's norm—suggesting cautious institutional positioning despite the bullish tone.
Business Wire · 09/29
⚡ DIVERGENCEAnalyst sees Alnylam's heart drug as undervalued after rival trial stumble
The bullish reframe clashes with the stock's recent 18% slide, yet options traders remain call-heavy with minimal squeeze pressure, indicating they are not rushing to bet on a rebound—a sign of skepticism beneath the headline optimism.
Seeking Alpha · 09/28
RNA therapeutics sector gaining traction; Alnylam among leaders
The upbeat sector story aligns with a call-heavy options lean, but no new material positions have opened, and off-exchange volume is below normal—suggesting the bullish narrative has not yet triggered fresh institutional buying.
Zacks Investment Research · 09/28
⚡ DIVERGENCEWall Street analysts overwhelmingly bullish on Alnylam stock
Analyst enthusiasm is strong, and options traders do favor calls over puts, but the lack of new open interest and below-average off-exchange activity suggest institutions are not aggressively following the buy calls—a potential divergence between Wall Street talk and institutional action.
The Motley Fool · 09/28
Alnylam vs. Tango Therapeutics: head-to-head comparison
The comparative analysis is neutral in tone, and options positioning remains balanced at the call-heavy end with no new large bets, reflecting a wait-and-see stance from options traders.
Defense World · 09/23
What is a “divergence”?
A divergence is when the news narrative and the institutional money flow point in opposite directions — a bearish headline while large call premium is bought, or heavy dark-pool selling under a bullish story. It signals the crowd and the desks may disagree.
How to read these numbers
Dark-pool volume — The share of trading executed off-exchange, at wholesalers and dark pools. About half of all US share volume prints there on an ordinary day, so the level by itself says almost nothing. What carries information is the distance from this name’s own recent norm, and whether the off-exchange size ran above its usual.
Off-exchange short share — How much of that off-exchange volume was sold short. The median across all listed names is about 49%, because wholesalers filling retail buy orders sell short and cover later. A reading near half is plumbing, not a bearish vote — compare it to the same name’s own 20-day norm.
Max pain — The price where the most options expire worthless — positioning often gravitates toward it near expiry.
Call wall / Put floor — Strikes with the heaviest call/put open interest — they often act as short-term resistance and support.
Put/Call ratio — Below ~0.7 leans bullish (more calls); above ~1 leans defensive (more puts).